王靖文,黄晓程,李璐婷,姚志湘,粟晖,李彦青

• 1:广西科技大学生物与化学工程学院
• 2:广西糖资源绿色加工重点实验室(广西科技大学)

摘要(Abstract)：

本研究以芳基二硫醚为原料，在乙酸溶剂中，使用质量分数为10%的次氯酸钠（NaClO）水溶液作为氧化剂，合成芳基磺酰氯；以二苯基二硫醚为模型底物，系统考察了溶剂种类、反应温度和NaClO水溶液用量（物质的量）对目标产物产率的影响，从而确定最佳反应条件：质量分数为10%的NaClO水溶液与芳基二硫醚的物质的量比为5:1，以乙酸为溶剂，在反应温度为15℃条件下反应1 min，可获得产率为52%～75%的相应芳基磺酰氯产物。所有产物结构均经氢-1核磁共振波谱法（~1H NMR）、碳-13核磁共振波谱法（~(13)C NMR）及气相色谱-质谱法（GC-MS）表征确证。本方法具有反应速度快、操作简便、底物适用范围广等优点，为从二硫醚中制备磺酰氯提供了一条便捷、高效的合成路径。

关键词(KeyWords)： 次氯酸钠;乙酸;磺酰氯;二硫醚;氧化氯化

Abstract:

Keywords:

基金项目(Foundation): 广西科技大学博士基金项目（校科博14Z05）;; 广西科技计划项目（2022AC21032）资助

作者(Author): 王靖文,黄晓程,李璐婷,姚志湘,粟晖,李彦青

DOI: 10.16375/j.cnki.cn45-1395/t.2026.03.015

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